PIPELINE
ARVAX advances a focused portfolio of longevity programs targeting the biological hallmarks of aging — cellular energy, inflammation, and neuroprotection.

Each program follows our translational model: rigorous biomarker strategy, rapid ANZ initiation under CTN/CTX, and globally credible human data.
  • AV-1959R — Alzheimer’s Prevention Vaccine
    A next-generation active immunotherapy designed to prevent or delay Alzheimer’s disease by inducing a targeted immune response against amyloid-beta.

    Status: Phase 1 clinical study underway at CMAX (Adelaide, Australia).
    Objectives: Safety, dose response, and immunogenicity, with exploratory neuroinflammatory biomarkers.
    Goal: To establish early proof of mechanism for a scalable, preventive approach to neurodegeneration
  • MitoRegen-1 — Mitochondrial Bio-Resilience Modulator
    An oral small molecule aimed at restoring mitochondrial efficiency and cellular energy balance associated with aging, fatigue, and muscle decline.

    Status: Pre-IND; IND-enabling toxicology and formulation studies ongoing (2025).
    Planned FIH: 2026 (Australia).
    Goal: Demonstrate safety, PK/PD correlation, and bioenergetic biomarker modulation in early human studies.
  • Senolyze-X — Selective Senotherapeutic Peptide Complex
    A proprietary peptide complex that selectively clears senescent cells through BCL-xL degradation and FOXO4-p53 pathway modulation.

    Status: IND targeted for mid-2026; first-in-human study expected late 2026 (ANZ).
    Goal: Establish tolerability and biomarker shifts in metabolic and frailty-related endpoints.
Pipeline Expansion
ARVAX continuously sources and evaluates early-stage longevity assets through partnerships with academic centers, biotech founders, and R&D institutions.
Our focus includes vaccines, small molecules, and peptide therapeutics addressing inflammation, mitochondrial function, and neurodegeneration.

Partner with us to explore how your discovery can become a first-in-human program within the ARVAX ecosystem.
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Investments in early-stage biotechnology, vaccines, and preventive medicine companies involve a high degree of risk, including the potential loss of invested capital. Past performance is not indicative of future results, and there can be no assurance that any investment strategy will achieve its objectives.
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